He’ll team up with Foo Fighters bandmate Taylor Hawkins to honour the Canadian trio, who finally made the Rock Hall cut last year.
Eagles man Don Henley will induct Randy Newman on the same night while Gary Clark Jr and John Mayer will lead the tribute to Albert King.
Heart will also be inducted, while Deep Purple were shortlisted but not voted in.
Meanwhile, Grohl has admitted it was a challenge to keep secret the fact that the surviving members of Nirvana had recorded a song with Paul McCartney for the documentary movie Sound City.
The film tells the story of the studio where Nirvana recorded Nevermind and includes interviews with many other big names who worked there, including Stevie Nicks, Neil Young and Tom Petty.
Macca teamed up with Grohl, Krist Novoselic and Pat Smear to create the track Cut Me Some Slack, which they later performed in New York and released as a single.
The drummer tells Billboard: “The McCartney song was the biggest secret. A few things leaked out, but we couldn’t give that away because this is – spoiler alert – THE moment.
“At the first few test screenings we did, the moment where Paul appears there were audible gasps in the room. When we were editing that segment, I said ‘I don’t want a ‘holy shit’ moment – I want a ‘holy fuck!’ moment.’ It really creates a cool moment.”
Unsurprisingly, Grohl cherished the opportunity to work with McCartney and others. He reflects: “That generation of musicians cherish, respect and value the practice of just going into a room and coming up with something – jamming it and making it a song.
“There’s not like seven songwriters and seven producers and digital technology or whatever. It’s people getting in a room.”